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Cayman StA-IFN-1
List Price
$481.00
Your Price
$481.00
Cayman StA-IFN-1 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-22402-10
MFG.PART:
22402-10
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
StA-IFN-1 is an inhibitor of the interferon (IFN) induction pathway with an IC50 value of 4.1 µM in a GFP reporter assay for IFN induction similar to TPCA-1 (Item No. 15115), which specifically inhibits the IKKβ component of the IFN induction pathway.1 It does not show inhibitory activity in a GFP reporter assay for IFN signaling in which ruxolitinib (Item No. 11609), which is specific for the IFN signaling component JAK1, is active. StA-IFN-1 reduces the levels of IFN-β, but not ISG MxA, mRNA, suggesting that it is selective for the IFN induction pathway and not the IFN signaling pathway.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-
CAS Number
300839-31-0
Molecular Formula
C14H13N3O2
Formula Weight
255.3
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 3 mg/mL
- DMSO: 5 mg/mL
- DMSO:PBS (pH 7.2) (1:10): 0.1 mg/mL
λmax
229, 305 nm
SMILES
O=C(C)N1C=C(C2C(C)=NNC2=O)C3=CC=CC=C31
InChi Code
InChI=1S/C14H13N3O2/c1-8-13(14(19)16-15-8)11-7-17(9(2)18)12-6-4-3-5-10(11)12/h3-7,13H,1-2H3,(H,16,19)
InChi Key
LWAAWXPHUVBIOH-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-22402-10 |
|---|---|
| Supplier Part Number | 22402-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 300839-31-0 |
| Energy Star | No |
| Green | No |
| Controlled | N |