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Cayman 9-Amino-6-chloro-2-methoxyacridine
List Price $81.00 Your Price $81.00
Cayman 9-Amino-6-chloro-2-methoxyacridine - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-22439-5
MFG.PART: 22439-5
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
9-Amino-6-chloro-2-methoxyacridine (ACMA) is a cell-permeable fluorescent probe that intercalates into DNA.1 It selectively binds to poly(dA-dT) sequences with the fluorescence lifetime decreasing with incorporation of guanosine. It is used for labeling DNA and displays excitation/emission spectra of 411/475 nm, respectively.2 ACMA fluorescence is pH-dependent and is quenched when a pH gradient is established, a property that has been utilized in animal- and plant-based studies.3,4,5 It also inhibits acetylcholinesterase with a Ki value of 49 nM.6
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
6-chloro-2-
CAS Number
3548-09-2
Synonyms
- ACMA
- NSC 15300
Molecular Formula
C14H11ClN2O
Formula Weight
258.7
Purity
≥98%
Emission
475 nm
Excitation
411 nm
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- Methanol: 1 mg/mL
- Water: miscible
λmax
218, 277, 340, 412, 435 nm
SMILES
ClC1=CC=C2C(N=C(C=CC(OC)=C3)C3=C2N)=C1
InChi Code
InChI=1S/C14H11ClN2O/c1-18-9-3-5-12-11(7-9)14(16)10-4-2-8(15)6-13(10)17-12/h2-7H,1H3,(H2,16,17)
InChi Key
IHHSSHCBRVYGJX-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-22439-5 |
|---|---|
| Supplier Part Number | 22439-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 3548-09-2 |
| Energy Star | No |
| Green | No |
| Controlled | N |