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Cayman KIN1400
List Price
$48.00
Your Price
$48.00
Cayman KIN1400 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-22441-1
MFG.PART:
22441-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
KIN1400 is a small molecule activator of the RIG-1-like receptor (RLR) pathway that has antiviral activity. It induces expression of the innate immune genes RIG-1, MDA5, IFIT1, IFIT2, IFITM1, OAS3, and Mx1 in THP-1 cells stimulated with phorbol 12-myristate 13-acetate (PMA; Item No. ). KIN1400 (20 μM) reduces West Nile and dengue viral RNA levels in HEK293 and Huh7 cells, respectively. It also inhibits hepatitis C virus (HCV) replication in a concentration-dependent manner in Huh7 cells.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
7-[(2-benzo
CAS Number
446826-86-4
Molecular Formula
C24H17F2N3O2S
Formula Weight
449.5
Purity
≥98%
Formulation
A solid
Solubility
- DMF: 30 mg/mL
- DMSO: 30 mg/mL
- DMSO:PBS (pH 7.2) (1:2): 0.3 mg/mL
- Ethanol: 2 mg/mL
SMILES
FC(F)OC(C=C1)=CC=C1C(NC2=NC3=C(C=CC=C3)S2)C4=C(O)C(N=CC=C5)=C5C=C4
InChi Code
InChI=1S/C24H17F2N3O2S/c25-23(26)31-16-10-7-15(8-11-16)20(29-24-28-18-5-1-2-6-19(18)32-24)17-12-9-14-4-3-13-27-21(14)22(17)30/h1-13,20,23,30H,(H,28,29)
InChi Key
YDSHHDISKUSKFW-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-22441-1 |
|---|---|
| Supplier Part Number | 22441-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 446826-86-4 |
| Energy Star | No |
| Green | No |
| Controlled | N |