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Cayman GAL-021
List Price
$49.00
Your Price
$49.00
Cayman GAL-021 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-22609-1
MFG.PART:
22609-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
GAL-021 is a large-conductance Ca2+-activated potassium channel (BKCa/KCa1.1) blocker. It inhibits BKCa single-channel activity in GH3 cells in a concentration-dependent manner when used at concentrations ranging from 1 to 10 μM. GAL-021 increases respiratory product minute volume in wild-type rats and mice (ED50s = 0.1 and 0.5 mg/kg) but not mice with bilaterally transected carotid sinus nerves or Slo-/- mice that lack the pore-forming α-subunit of BKCa. It reverses morphine-induced respiratory depression in rats and cynomolgus monkeys. GAL-021 also potentiates morphine-induced analgesia in a tail-flick assay in rats.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N2-methoxy-
CAS Number
1380341-99-0
Molecular Formula
C11H22N6O
Formula Weight
254.3
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 3 mg/mL
- DMSO: 5 mg/mL
- Ethanol: Slightly soluble
- PBS (pH 7.2): 0.30 mg/mL
SMILES
CN(OC)C1=NC(NCCC)=NC(NCCC)=N1
InChi Code
InChI=1S/C11H22N6O/c1-5-7-12-9-14-10(13-8-6-2)16-11(15-9)17(3)18-4/h5-8H2,1-4H3,(H2,12,13,14,15,16)
InChi Key
FJNLCHNQVJVCPY-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-22609-1 |
|---|---|
| Supplier Part Number | 22609-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1380341-99-0 |
| Energy Star | No |
| Green | No |
| Controlled | N |