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Cayman Bexarotene-d4
List Price
$334.00
Your Price
$334.00
Cayman Bexarotene-d4 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-22610-1
MFG.PART:
22610-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Bexarotene-d4 is intended for use as an internal standard for the quantification of bexarotene (Item No. ) by GC- or LC-MS. Bexarotene is a high-affinity ligand for retinoid X receptors (RXRs) (EC50s = 28, 25, and 20 nM for RXRα, β, and γ, respectively). It inhibits cell cycle progression, induces apoptosis, prevents or overcomes multidrug resistance through multidrug resistance protein 1 (MDR1), and blocks angiogenesis and metastasis, making it a promising chemopreventive agent against cancer., Bexarotene also, through RXR activation, stimulates clearance of soluble β-amyloid, reduces plaque area, and reverses deficits related to Alzheimer’s disease in mice.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-
CAS Number
2182068-00-2
Molecular Formula
C24H24D4O2
Formula Weight
352.5
Purity
≥99% deuterated forms (d1-d4)
Formulation
A crystalline solid
Solubility
- DMF: 20 mg/mL
- DMF:PBS (pH 7.2)(1:3): 0.25 mg/mL
- DMSO: 10 mg/mL
- Ethanol: 0.5 mg/mL
λmax
260 nm
SMILES
C=C(C1=C([2H])C([2H])=C(C(O)=O)C([2H])=C1[2H])C2=CC3=C(C=C2C)C(C)(C)CCC3(C)C
InChi Code
InChI=1S/C24H28O2/c1-15-13-20-21(24(5,6)12-11-23(20,3)4)14-19(15)16(2)17-7-9-18(10-8-17)22(25)26/h7-10,13-14H,2,11-12H2,1,3-6H3,(H,25,26)/i7D,8D,9D,10D
InChi Key
NAVMQTYZDKMPEU-ULDPCNCHSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-22610-1 |
|---|---|
| Supplier Part Number | 22610-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | Canada |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 2182068-00-2 |
| Energy Star | No |
| Green | No |
| Controlled | N |