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Cayman IWP-12
List Price
$520.00
Your Price
$520.00
Cayman IWP-12 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-22729-25
MFG.PART:
22729-25
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
IWP-12 is a small molecule inhibitor of porcupine (PORCN), which is an acyltransferase that palmitoylates and activates Wnt proteins.1 IWP-12 inhibits cell-autonomous Wnt signaling with an IC50 value of 15 nM.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-(6 -methyl-2-ben zothiazolyl)- 2-[(3,4,6,7- tetrahydro-3, 6-dimethyl-4- oxothieno[3,2- d]pyrimidin-2 -yl)thio]-ace tamide
CAS Number
688353-45-9
Synonyms
- Inhibitor of Wnt Production-12
Molecular Formula
C18H18N4O2S3
Formula Weight
418.6
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 5 mg/mL
- DMF:PBS(pH7.2) (1:2): 0.3 mg/mL
- DMSO: 2 mg/mL
λmax
278, 302, 335 nm
SMILES
O=C(CSC(N1C)=NC2=C(SC(C)C2)C1=O)NC3=NC4=C(C=C(C)C=C4)S3
InChi Code
InChI=1S/C18H18N4O2S3/c1-9-4-5-11-13(6-9)27-17(19-11)21-14(23)8-25-18-20-12-7-10(2)26-15(12)16(24)22(18)3/h4-6,10H,7-8H2,1-3H3,(H,19,21,23)
InChi Key
RBFDSBJDWZOTGR-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-22729-25 |
|---|---|
| Supplier Part Number | 22729-25 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 688353-45-9 |
| Energy Star | No |
| Green | No |
| Controlled | N |