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Cayman C2 Phytoceramide (t18:0/2:0)
List Price
$236.00
Your Price
$236.00
Cayman C2 Phytoceramide (t18:0/2:0) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-22823-5
MFG.PART:
22823-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
C2 Phytoceramide is a bioactive semisynthetic sphingolipid that inhibits formyl peptide-induced oxidant release (IC50 = 0.38 µM) in suspended polymorphonuclear cells. It increases COX-2 protein levels 15-fold through ERK signaling. It induces death of keratinocytes (20% viability) with an ED50 value of 30 µM, the same concentration at which 35% of cells in a TUNEL assay are apoptotic. C2 Phytoceramide also has antiproliferative effects in CHO Cells, with greater than 80% cytotoxicity achieved at a concentration of 20 µM, and induces internucleosomal DNA fragmentation. In addition, it inhibits the activation of phospholipase D (PLD) mediated by muscarinic acetylcholine receptors in vitro. [Matreya, LLC. Catalog No. 1897]
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[(1S,2S,3R)
CAS Number
21830-28-4
Synonyms
- N-Acetyl Phytosphingosine
- C2:0 Phytoceramide
- Cer(t18:0/2:0)
- Ceramide (t18:0/2:0)
- NAPS
Molecular Formula
C20H41NO4
Formula Weight
359.6
Purity
≥98%
Formulation
A solid
Solubility
- DMSO: Soluble
- Ethanol: Soluble
- Methanol: Soluble
SMILES
OC[C@H](NC(C)=O)[C@@H]([C@@H](CCCCCCCCCCCCCC)O)O
InChi Code
InChI=1S/C20H41NO4/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-19(24)20(25)18(16-22)21-17(2)23/h18-20,22,24-25H,3-16H2,1-2H3,(H,21,23)/t18-,19+,20-/m0/s1
InChi Key
SZUJJDLBXJCDNT-ZCNNSNEGSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-22823-5 |
|---|---|
| Supplier Part Number | 22823-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 21830-28-4 |
| Energy Star | No |
| Green | No |
| Controlled | N |