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Cayman 2-C-Methylcytidine
List Price $178.00 Your Price $178.00
Cayman 2-C-Methylcytidine - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-22887-10
MFG.PART: 22887-10
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
2-C-Methylcytidine (2CMC) is a ribonucleoside with broad-spectrum antiviral activity. It reduces the number of viral plaques in BHK-21 cells infected with dengue type 2, reovirus type 1, West Nile, and yellow fever RNA viruses with EC50 values of 95, 26, 80, and 75 μM, respectively. 2CMC inhibits hepatitis C virus (HCV) replication (EC50 = 2.2 μM in a replicon assay) and protects MDBK cells from infection with bovine virus diarrhea virus (BVDV; EC50 = 2.2 μM) and human coronavirus (HCoV; EC50 = 90 μM). It also reduces infectious virus yield in BHK-21 cells infected with foot-and-mouth disease virus (FMDV; EC50 = 6.4 μM) and swine vesicular disease virus (SVDV; EC50 = 45.2 μM). In vivo, 2CMC reduces viral shedding to undetectable levels in a mouse model of persistent norovirus infection.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-C-
CAS Number
20724-73-6
Synonyms
- 2CMC
Molecular Formula
C10H15N3O5
Formula Weight
257.2
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 10 mg/mL
- DMSO: 20 mg/mL
- PBS (pH 7.2): 10 mg/mL
λmax
275 nm
SMILES
O=C(N=C(N)C=C1)N1[C@H]2[C@](C)(O)[C@H](O)[C@@H](CO)O2
InChi Code
InChI=1S/C10H15N3O5/c1-10(17)7(15)5(4-14)18-8(10)13-3-2-6(11)12-9(13)16/h2-3,5,7-8,14-15,17H,4H2,1H3,(H2,11,12,16)/t5-,7-,8-,10-/m1/s1
InChi Key
PPUDLEUZKVJXSZ-VPCXQMTMSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-22887-10 |
|---|---|
| Supplier Part Number | 22887-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 20724-73-6 |
| Energy Star | No |
| Green | No |
| Controlled | N |