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Cayman YYA-021
List Price
$36.00
Your Price
$36.00
Cayman YYA-021 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-22915-1
MFG.PART:
22915-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
YYA-021 is a small molecule CD4 mimetic that competitively inhibits gp120 from interacting with CD4, preventing HIV entry into cells. It inhibits infection of PM1/CCR5 cells from lab isolates of the HIV-1 strains IIIB (X4, Sub B) and 89.6 (dual, Sub B) (IC50s = 23 and 41 µM, respectively) as well as clinical isolates of the fTOI (R5, Sub B) and KYAG strains (R5, Sub B) (IC50s = 16 and 51 µM, respectively). It also inhibits HIV-1 infection of TZM-bl cells (IC50 = 8.4 µM) and reduces viability of mock-infected PM1/CCR5 cells with cytotoxic concentration (CC50) values of 260 µM.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N1-(4-methylphenyl)-N2-(2,2,6,6-tetramethyl-4-piperidinyl)-ethanediamide
CAS Number
144217-65-2
Molecular Formula
C18H27N3O2
Formula Weight
317.4
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 12 mg/mL
- DMF:PBS (pH7.2) (1:30): 0.03 mg/mL
- DMSO: 5 mg/mL
- Ethanol: 0.125 mg/mL
λmax
276 nm
SMILES
CC1(C)CC(NC(C(NC2=CC=C(C)C=C2)=O)=O)CC(C)(C)N1
InChi Code
InChI=1S/C18H27N3O2/c1-12-6-8-13(9-7-12)19-15(22)16(23)20-14-10-17(2,3)21-18(4,5)11-14/h6-9,14,21H,10-11H2,1-5H3,(H,19,22)(H,20,23)
InChi Key
AYAGJQPDCPRMNG-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-22915-1 |
|---|---|
| Supplier Part Number | 22915-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 144217-65-2 |
| Energy Star | No |
| Green | No |
| Controlled | N |