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Cayman 11-deoxy Corticosterone
List Price $141.00 Your Price $141.00
Cayman 11-deoxy Corticosterone - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-22916-100
MFG.PART: 22916-100
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
11-deoxy Corticosterone (DOC) is an endogenous mineralocorticoid synthesized in the zona fasciculata and zona glomerulosa of the adrenal gland. It is a metabolite of progesterone (Item No. ) and precursor to aldosterone (Item No. ) and corticosterone (Item No. ). DOC is metabolized to the neuroactive compound (3α,5α)-2,21-dihydroxypregnan-20-one (THDOC), which positively modulates GABAA receptors and produces effects similar to barbiturates in rats. Injections of naloxone (Item Nos. | ) and corticotropin-releasing hormone (CRH) increase, while dexamethasone decreases, DOC in cynomolgus monkeys. DOC levels are increased 3.4-fold in obese and diabetic mice.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
21-hydroxy-
CAS Number
64-85-7
Synonyms
- DOC
- NSC 11319
- 21-hydroxy Progesterone
Molecular Formula
C21H30O3
Formula Weight
330.5
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMF: 25 mg/mL
- DMSO: 25 mg/mL
- Ethanol: 25 mg/mL
- Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/mL
λmax
240 nm
SMILES
O=C1CC[C@@]2(C)C(CC[C@]3([H])[C@]2([H])CC[C@@]4(C)[C@@]3([H])CC[C@@H]4C(CO)=O)=C1
InChi Code
InChI=1S/C21H30O3/c1-20-9-7-14(23)11-13(20)3-4-15-16-5-6-18(19(24)12-22)21(16,2)10-8-17(15)20/h11,15-18,22H,3-10,12H2,1-2H3/t15-,16-,17-,18+,20-,21-/m0/s1
InChi Key
ZESRJSPZRDMNHY-YFWFAHHUSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-22916-100 |
|---|---|
| Supplier Part Number | 22916-100 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 64-85-7 |
| Energy Star | No |
| Green | No |
| Controlled | N |