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Cayman SBC-110736
List Price
$41.00
Your Price
$41.00
Cayman SBC-110736 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-23103-1
MFG.PART:
23103-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
SBC-110736 is an inhibitor of proprotein convertase subtilisin kexin type 9 (PCSK9). It increases LDL receptor (LDLR) levels in HepG2 cells expressing PCSK9 when used at a concentration of 400 nM. SBC-110736 (8 mg/kg per day) reduces plasma total cholesterol levels by a mean of 38% in mice fed a high-fat diet. It also reduces plasma LDL cholesterol levels in mice fed a high-fat diet and exhibits an additive effect when administered in combination with atorvastatin (Item No. ).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[4-[[4-(4-
CAS Number
1629166-02-4
Molecular Formula
C26H27N3O2
Formula Weight
413.5
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 15 mg/mL
- DMF:PBS (pH 7.2) (1:4): 0.20 mg/mL
- DMSO: 10 mg/mL
λmax
253 nm
SMILES
CC1=CC=C(N2CCN(C(C3=CC=C(NC(C)=O)C=C3)=O)C(C4=CC=CC=C4)C2)C=C1
InChi Code
InChI=1S/C26H27N3O2/c1-19-8-14-24(15-9-19)28-16-17-29(25(18-28)21-6-4-3-5-7-21)26(31)22-10-12-23(13-11-22)27-20(2)30/h3-15,25H,16-18H2,1-2H3,(H,27,30)
InChi Key
PILMFSWQYWYOJC-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-23103-1 |
|---|---|
| Supplier Part Number | 23103-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1629166-02-4 |
| Energy Star | No |
| Green | No |
| Controlled | N |