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Cayman RN-18
List Price $41.00 Your Price $41.00
Cayman RN-18 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-23331-1
MFG.PART: 23331-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
RN-18 is an inhibitor of HIV-1 viral infectivity factor (Vif), an HIV-1 regulatory protein that does not have cellular homologs. RN-18 inhibits Vif-mediated degradation of the DNA editing enzyme APOBEC3G with IC50 values of 10-30 µM in a high-throughput fluorescence screen. It inhibits viral replication of HIV-1 with IC50 values of 4.5 and 10 µM for nonpermissive CEM and H9 cells, respectively, and >100 µM for permissive cells.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-(2-methoxy
CAS Number
431980-38-0
Molecular Formula
C20H16N2O4S
Formula Weight
380.4
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/mL
- DMSO: 30 mg/mL
- DMSO:PBS (pH 7.2) (1:2): 0.33 mg/mL
- Ethanol: slightly soluble
λmax
332 nm
SMILES
O=C(NC1=C(OC)C=CC=C1)C2=CC=CC=C2SC3=CC=C([N+]([O-])=O)C=C3
InChi Code
InChI=1S/C20H16N2O4S/c1-26-18-8-4-3-7-17(18)21-20(23)16-6-2-5-9-19(16)27-15-12-10-14(11-13-15)22(24)25/h2-13H,1H3,(H,21,23)
InChi Key
JKNUDHUHXMELIJ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-23331-1 |
|---|---|
| Supplier Part Number | 23331-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 431980-38-0 |
| Energy Star | No |
| Green | No |
| Controlled | N |