We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn about our cookie policy.
Cayman NSC 5844
List Price $653.00 Your Price $653.00
Cayman NSC 5844 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-23443-50
MFG.PART: 23443-50
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
NSC 5844 is a bis-quinoline with diverse biological activities.1,2,3 It inhibits the growth of P. falciparum strains that are sensitive (D-6) and resistant (W-2) to chloroquine (Item No. 14194) in vitro (IC50s = 17 and 27 nM, respectively) but lacks activity against P. berghei in vivo.1 NSC 5844 inhibits the growth of MDA-MB-468 and MCF-7 breast cancer cells with GI50 values of 7.35 and 14.80 μM, respectively.2 It also inhibits 24% of botulinum neurotoxin serotype A light chain (BoNT/A LC) metalloprotease activity at a concentration of 20 μM.3
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N1,N2-bis
CAS Number
140926-75-6
Molecular Formula
C20H16Cl2N4
Formula Weight
383.3
Purity
≥95%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 0.33 mg/mL
- DMSO: 0.25 mg/mL
- Ethanol: Slightly soluble
λmax
219, 254, 336 nm
SMILES
ClC1=CC=C(C(NCCNC2=CC=NC3=C2C=CC(Cl)=C3)=CC=N4)C4=C1
InChi Code
InChI=1S/C20H16Cl2N4/c21-13-1-3-15-17(5-7-23-19(15)11-13)25-9-10-26-18-6-8-24-20-12-14(22)2-4-16(18)20/h1-8,11-12H,9-10H2,(H,23,25)(H,24,26)
InChi Key
SSXYXSMMVMVYEV-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-23443-50 |
|---|---|
| Supplier Part Number | 23443-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 140926-75-6 |
| Energy Star | No |
| Green | No |
| Controlled | N |