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Cayman Tasimelteon
List Price $163.00 Your Price $163.00
Cayman Tasimelteon - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-23546-50
MFG.PART: 23546-50
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Tasimelteon is a melatonin (MT) receptor agonist.1 It selectively binds MT1 and MT2 receptors (Kis = 0.304 and 0.069 nM, respectively, in NIH3T3 cells expressing the recombinant human receptors) over a panel of 160 additional receptors and enzymes at 10 µM. Tasimelteon inhibits forskolin-induced cAMP accumulation with EC50 values of 0.79 and 1 nM in NIH3T3 cells expressing the MT1 or MT2 receptor, respectively. Formulations containing tasimelteon have been used in the treatment of non-24-hour sleep-wake disorder.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[[(1R,2R)-
CAS Number
609799-22-6
Synonyms
- BMS 214778
Molecular Formula
C15H19NO2
Formula Weight
245.3
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/mL
- DMSO: 30 mg/mL
- Ethanol: 30 mg/mL
λmax
287 nm
SMILES
O=C(CC)NC[C@@H]1C[C@H]1C2=C3C(OCC3)=CC=C2
InChi Code
InChI=1S/C15H19NO2/c1-2-15(17)16-9-10-8-13(10)11-4-3-5-14-12(11)6-7-18-14/h3-5,10,13H,2,6-9H2,1H3,(H,16,17)/t10-,13+/m0/s1
InChi Key
PTOIAAWZLUQTIO-GXFFZTMASA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-23546-50 |
|---|---|
| Supplier Part Number | 23546-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 609799-22-6 |
| Energy Star | No |
| Green | No |
| Controlled | N |