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Cayman Butoconazole (Nitrate); Purity- Greater Than Or Equal To 9
List Price
$32.00
Your Price
$32.00
Cayman Butoconazole (Nitrate); Purity- Greater Than Or Equal To 98%; Size- 500 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-23554-500
MFG.PART:
23554-500
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Brinzolamide is a potent inhibitor of carbonic anhydrase II (CAII) and CAIV (IC50s = 3.19 and 45.3 nM, respectively). It is selective for CAII and CAIV over CAI (IC50 = ~1,365 nM). Brinzolamide (30 mg/kg) reduces intestinal charcoal meal progression by 44% and prolongs pentobarbital sodium-induced sleep time by 35% in mice. Topical administration of brinzolamide (0.25, 0.5, and 1 mg/eye) reduces intraocular pressure (IOP) in a rabbit model of spontaneous ocular hypertension. It also reduces IOP in a cynomolgus monkey model of argon laser trabeculoplasty-induced ocular hypertension. Formulations containing brinzolamide have been used in the treatment of glaucoma and ocular hypertension.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4R-
CAS Number
138890-62-7
Synonyms
- AL 4862
Molecular Formula
C12H21N3O5S3
Formula Weight
383.5
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/ml
- DMSO: 30 mg/ml
- DMSO:PBS(pH 7.2) (1:2): 0.3 mg/ml
λmax
253 nm
SMILES
O=S(C1=CC2=C(S1)S(N(CCCOC)C[C@@H]2NCC)(=O)=O)(N)=O
InChi Code
InChI=1S/C12H21N3O5S3/c1-3-14-10-8-15(5-4-6-20-2)23(18,19)12-9(10)7-11(21-12)22(13,16)17/h7,10,14H,3-6,8H2,1-2H3,(H2,13,16,17)/t10-/m0/s1
InChi Key
HCRKCZRJWPKOAR-JTQLQIEISA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-23554-500 |
|---|---|
| Featured | No |
| Supplier Part Number | 23554-500 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 64872-77-1 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |