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Cayman Etofenamate
List Price $98.00 Your Price $98.00
Cayman Etofenamate - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-23674-50
MFG.PART: 23674-50
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Etofenamate is a non-steroidal anti-inflammatory drug (NSAID) and diethylene glycol ester form of flufenamic acid (Item No. 21447) that has anti-inflammatory and analgesic activities.1,2 It inhibits lipoxygenase isolated from guinea pig leukocytes (IC50 = 5.3 μM) and the production of prostaglandin E2 (PGE2; Item No. 14010) in stimulated rat peritoneal macrophages.2 In vivo, etofenamate reduces acetic acid-induced vascular permeability in mice and UV-induced erythema in guinea pigs in a dose-dependent manner at doses ranging from 40-320 and 5-20 mg/kg, respectively.1 Etofenamate (40 mg/kg per day for 21 days) inhibits inflammation in a rat model of adjuvant-induced arthritis. It also decreases the pain response in a silver nitrate-induced rat model of arthritis and the acetic acid-induced writhing test in mice, indicating analgesic activity. Formulations containing etofenamate have been used in the treatment of osteoarthritis.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-[[3-
CAS Number
30544-47-9
Molecular Formula
C18H18F3NO4
Formula Weight
369.3
Purity
≥98%
Formulation(Request formulation change)
A neat oil
Solubility(Learn about Variance in Solubility)
- DMF: 40 mg/mL
- DMSO: 40 mg/mL
- Ethanol: 50 mg/mL
- Ethanol:PBS(pH 7.2) (1:5): 0.1 mg/mL
λmax
205, 221, 287, 347 nm
SMILES
O=C(OCCOCCO)C1=C(NC2=CC=CC(C(F)(F)F)=C2)C=CC=C1
InChi Code
InChI=1S/C18H18F3NO4/c19-18(20,21)13-4-3-5-14(12-13)22-16-7-2-1-6-15(16)17(24)26-11-10-25-9-8-23/h1-7,12,22-23H,8-11H2
InChi Key
XILVEPYQJIOVNB-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-23674-50 |
|---|---|
| Supplier Part Number | 23674-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | Canada |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 30544-47-9 |
| Energy Star | No |
| Green | No |
| Controlled | N |