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Cayman Avobenzone
List Price $127.00 Your Price $127.00
Cayman Avobenzone - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-23836-10
MFG.PART: 23836-10
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Avobenzone is a full-spectrum ultraviolet A (UVA) blocker. It inhibits UVA-induced increases in melanin levels and tyrosinase activity in B16/F10 melanoma cells (IC30s = 21.94 and 24.25 μM, respectively). Avobenzone (30 μM) also inhibits UVA-induced production of reactive oxygen species (ROS) and 8-hydroxy-2-deoxyguanosine (8-OH-dG; Item No. ), as well as inhibits UVA-induced depletion of glutathione (GSH; Item No. ), in B16/F10 cells. It increases nuclear translocation of nuclear factor erythroid 2-related factor 2 (Nrf2) and upregulates the antioxidant response element (ARE) in UVA-irradiated B16/F10 cells when used at at a concentration of 30 μM. Formulations containing avobenzone have been used as a sun protectant in sunscreen products.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1-[4-(1,1-di
CAS Number
70356-09-1
Synonyms
- BMDBM
- Butyl Methoxydibenzoylmethane
Molecular Formula
C20H22O3
Formula Weight
310.4
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/mL
- DMSO: 30 mg/mL
- DMSO:PBS (pH 7.2) (1:2): 0.33 mg/mL
- Ethanol: 5 mg/mL
λmax
363 nm
SMILES
CC(C)(C)C1=CC=C(C(CC(C2=CC=C(OC)C=C2)=O)=O)C=C1
InChi Code
InChI=1S/C20H22O3/c1-20(2,3)16-9-5-14(6-10-16)18(21)13-19(22)15-7-11-17(23-4)12-8-15/h5-12H,13H2,1-4H3
InChi Key
XNEFYCZVKIDDMS-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-23836-10 |
|---|---|
| Supplier Part Number | 23836-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 70356-09-1 |
| Energy Star | No |
| Green | No |
| Controlled | N |