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Cayman Lalistat 1
List Price
$49.00
Your Price
$49.00
Cayman Lalistat 1 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-23891-1
MFG.PART:
23891-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Lalistat 1 is an inhibitor of lysosomal acid lipase (LAL; IC50 = 68 nM using purified human LAL). It is selective for LAL over human pancreatic and bovine milk lipoprotein lipases up to a concentration of 10 µM. Lalistat 1 (0.01-10 µM) reduces cholesterol accumulation in lysosome-like storage organelles in GM03123 human fibroblast cells deficient in NPC1, a membrane protein found in late endosomes, in a concentration-dependent manner but has little effect on cholesterol accumulation in NPC1-deficient CHO Cells.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
4-morpholine carboxylic acid, 4-(1-piperi dinyl)-1,2,5- thiadiazol- 3-yl ester
CAS Number
501104-16-1
Molecular Formula
C12H18N4O3S
Formula Weight
298.4
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 20 mg/mL
- DMSO: 20 mg/mL
- Ethanol: 20 mg/mL
- Ethanol:PBS(pH 7.2) (1:5): 0.16 mg/mL
λmax
302 nm
SMILES
O=C(N1CCOCC1)OC2=NSN=C2N3CCCCC3
InChi Code
InChI=1S/C12H18N4O3S/c17-12(16-6-8-18-9-7-16)19-11-10(13-20-14-11)15-4-2-1-3-5-15/h1-9H2
InChi Key
XAWUWPUYJUOUOF-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-23891-1 |
|---|---|
| Supplier Part Number | 23891-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 501104-16-1 |
| Energy Star | No |
| Green | No |
| Controlled | N |