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Cayman Lipoxin B4 methyl ester
List Price $686.00 Your Price $686.00
Cayman Lipoxin B4 methyl ester - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-24073-50
MFG.PART: 24073-50
UNSPSC: 12352200
Manufacturer: Cayman


Product Description
Lipoxin B4 (LXB4) methyl ester is a lipid soluble prodrug form of the transcellular metabolite LXB4 (Item No. 90420). LXB4 is a positional isomer of LXA4 (Item No. 90410) produced by the metabolism of 15-HETE (Item No. 34700) or 15-HpETE (Item No. 44720) by human leukocytes.1,2 At a concentration of 100 nM, LXB4 inhibits polymorphonuclear leukocyte (PMN) migration stimulated by leukotriene B4 (LTB4; Item No. 20110) and inhibits LTB4-induced adhesion of PMNs with an IC50 value of 0.3 nM.3
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5S,14R,15S- trihydroxy- 6E,8Z,10E, 12E-eicosa tetraenoic acid, methyl ester
CAS Number
97589-07-6
Synonyms
- LXB4 methyl ester
Molecular Formula
C21H34O5
Formula Weight
366.5
Purity
≥95%
Formulation(Request formulation change)
A solution in ethanol
Solubility(Learn about Variance in Solubility)
- DMF: 50 mg/mL
- DMSO: unstable
- Ethanol: 50 mg/mL
- PBS (pH 7.2): 1 mg/mL
λmax
221, 289, 301, 316 nm
SMILES
O[C@@H](CCCC(OC)=O)/C=C/C=C\C=C\C=C\[C@@H](O)[C@@H](O)CCCCC
InChi Code
InChI=1S/C21H34O5/c1-3-4-9-15-19(23)20(24)16-11-8-6-5-7-10-13-18(22)14-12-17-21(25)26-2/h5-8,10-11,13,16,18-20,22-24H,3-4,9,12,14-15,17H2,1-2H3/b7-5-,8-6+,13-10+,16-11+/t18-,19+,20-/m1/s1
InChi Key
HXIJZYQKEFLJAL-BMNOQHBCSA-N
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
Stability
≥ 1 year
| SKU | CAYM-24073-50 |
|---|---|
| Supplier Part Number | 24073-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -80 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 97589-07-6 |
| Energy Star | No |
| Green | No |
| Controlled | N |

