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Cayman Ombitasvir
List Price $218.00 Your Price $218.00
Cayman Ombitasvir - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-24116-1
MFG.PART: 24116-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Ombitasvir is an orally bioavailable and potent inhibitor of the hepatitis C virus (HCV) non-structural protein 5A (NS5A)., It reduces HCV replication in stable replicon cell lines with EC50 values ranging from 0.82 to 19.3 pM against genotypes 1a, 1b, 2a, 2b, 3a, 4a, and 5a and an EC50 value of 366 pM for genotype 6a., Against subgenomic replicons from clinical isolates of genotypes 1a-6a expressed in Huh-7 derived cells, ombitasvir inhibits HCV replication with EC50 values ranging from 0.1 pM for genotype 4a to 68 pM for genotype 6a. Formulations containing ombitasvir have been used in the treatment of HCV genotypes 1 and 4.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2,2-[[(2S,5S)-
CAS Number
1258226-87-7
Synonyms
- ABT-267
Molecular Formula
C50H67N7O8
Formula Weight
894.1
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 30 mg/mL
- DMSO: 30 mg/mL
- Ethanol: 30 mg/mL
- Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/mL
λmax
252 nm
SMILES
CC(C)(C)C(C=C1)=CC=C1N2[C@H](C3=CC=C(NC([C@@H]4CCCN4C([C@@H](NC(OC)=O)C(C)C)=O)=O)C=C3)CC[C@H]2C5=CC=C(NC([C@H]6N(C([C@@H](NC(OC)=O)C(C)C)=O)CCC6)=O)C=C5
InChi Code
InChI=1S/C50H67N7O8/c1-30(2)42(53-48(62)64-8)46(60)55-28-10-12-40(55)44(58)51-35-20-14-32(15-21-35)38-26-27-39(57(38)37-24-18-34(19-25-37)50(5,6)7)33-16-22-36(23-17-33)52-45(59)41-13-11-29-56(41)47(61)43(31(3)4)54-49(63)65-9/h14-25,30-31,38-43H,10-13,26-29H2,1-9H3,(H,51,58)(H,52,59)(H,53,62)(H,54,63)/t38-,39-,40-,41-,42-,43-/m0/s1
InChi Key
PIDFDZJZLOTZTM-KHVQSSSXSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-24116-1 |
|---|---|
| Supplier Part Number | 24116-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1258226-87-7 |
| Energy Star | No |
| Green | No |
| Controlled | N |