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Cayman P7C3-A20
List Price
$40.00
Your Price
$40.00
Cayman P7C3-A20 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-24201-1
MFG.PART:
24201-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
P7C3-A20 is a derivative of P7C3 (Item No. ) that has proneurogenic and neuroprotective activity. It increases proliferation in the subgranular zone (SGZ) of the adult mouse dentate gyrus in a dose-dependent manner when administered at doses ranging from 0.1 to 10 µM. It also protects U2OS cells from calcium-induced mitochondrial dissolution. In a rat model of traumatic brain injury, P7C3-A20 (10 mg/kg, i.p., twice daily for one week) decreases contusion volume, increases proliferation in the SGZ, and decreases the latency to REACH the platform in the Morris water maze to sham surgery control levels. It also prevents or reverses dopaminergic cell death and motor deficits in a 6-OHDA rat model of Parkinson’s disease.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
3,6-dibromo-
CAS Number
1235481-90-9
Molecular Formula
C22H19Br2FN2O
Formula Weight
506.2
Purity
≥95%
Formulation
A crystalline solid
Solubility
- DMSO: 10 mm
λmax
212, 234, 242, 270, 302 nm
SMILES
BrC(C=C1)=CC2=C1N(CC(CNC3=CC(OC)=CC=C3)F)C4=CC=C(Br)C=C42
InChi Code
InChI=1S/C22H19Br2FN2O/c1-28-18-4-2-3-17(11-18)26-12-16(25)13-27-21-7-5-14(23)9-19(21)20-10-15(24)6-8-22(20)27/h2-11,16,26H,12-13H2,1H3
InChi Key
XNLTWMQBJFWQOU-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-24201-1 |
|---|---|
| Supplier Part Number | 24201-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1235481-90-9 |
| Energy Star | No |
| Green | No |
| Controlled | N |