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Cayman BI-2545
List Price
$204.00
Your Price
$204.00
Cayman BI-2545 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-24285-10
MFG.PART:
24285-10
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
BI-2545 is an inhibitor of autotaxin (IC50s = 2.2 and 3.4 for the human and rat enzyme, respectively).1 It is selective for autotaxin over a panel of 48 enzymes, transporters, ion channels, and receptors at 10 µM. BI-2545 (10 mg/kg) reduces plasma lysophosphatidic acid (LPA) levels in rats.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
3,5-bis(tri fluoromethyl) benzyl (1R, 5S,6s)-6- ((1H-benzo[d] [1,2,3] triazole-6- carboxamido) methyl)-3- azabicyclo [3.1.0]hexane- 3-carboxylate
CAS Number
2162961-71-7
Molecular Formula
C23H19F6N5O3
Formula Weight
527.4
Purity
≥98%
Formulation(Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
- DMSO: soluble
λmax
213 nm
SMILES
[H][C@]12[C@](CN(C(OCC3=CC(C(F)(F)F)=CC(C(F)(F)F)=C3)=O)C2)([H])[C@@H]1CNC(C4=CC(N=NN5)=C5C=C4)=O
InChi Code
InChI=1S/C23H19F6N5O3/c24-22(25,26)13-3-11(4-14(6-13)23(27,28)29)10-37-21(36)34-8-16-15(17(16)9-34)7-30-20(35)12-1-2-18-19(5-12)32-33-31-18/h1-6,15-17H,7-10H2,(H,30,35)(H,31,32,33)/t15-,16-,17+
InChi Key
ZDOBSAPHUUUOHX-OSYLJGHBSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-24285-10 |
|---|---|
| Supplier Part Number | 24285-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 2162961-71-7 |
| Energy Star | No |
| Green | No |
| Controlled | N |