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Cayman UBP 302
List Price
$63.00
Your Price
$63.00
Cayman UBP 302 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-24309-1
MFG.PART:
24309-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
UBP 302 is an antagonist of glutamate receptor 5 (GluR5) subunit-containing kainate receptors that inhibits kainate-induced responses in isolated rat dorsal roots (Kd = 402 nM). In vitro, UBP 302 inhibits gamma frequency oscillations in the rat basolateral amygdala at a concentration of 25 µM, and blocks kainate receptor signaling in layer III neurons within the mouse medial entorhinal cortex at 20 µM, abrogating the intense synaptic activity characteristic of the Up state of cortical slow oscillation., In vivo, UBP 302 (250 mg/kg) significantly reduces seizure severity in a rat model of soman-induced status epilepticus.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
αS-amino-3- [(2-carboxy phenyl)methyl]- 3,4-dihydro- 2,4-dioxo- 1(2H)-pyrimidine propanoic acid
CAS Number
745055-91-8
Molecular Formula
C15H15N3O6
Formula Weight
333.3
Purity
≥98%
Formulation
A solid
Solubility
- DMSO: 50 mm
SMILES
O=C(O)C1=CC=CC=C1CN2C(N(C[C@H](N)C(O)=O)C=CC2=O)=O
InChi Code
InChI=1S/C15H15N3O6/c16-11(14(22)23)8-17-6-5-12(19)18(15(17)24)7-9-3-1-2-4-10(9)13(20)21/h1-6,11H,7-8,16H2,(H,20,21)(H,22,23)/t11-/m0/s1
InChi Key
UUIYULWYHDSXHL-NSHDSACASA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-24309-1 |
|---|---|
| Supplier Part Number | 24309-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 745055-91-8 |
| Energy Star | No |
| Green | No |
| Controlled | N |