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Cayman GM 1489
List Price $81.00 Your Price $81.00
Cayman GM 1489 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-24313-1
MFG.PART: 24313-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
GM 1489 is a broad-spectrum inhibitor of matrix metalloproteinases (MMPs) with Ki values of 0.002, 0.1, 0.5, 0.2, and 20 μM for MMP-1, MMP-8, MMP-2, MMP-9, and MMP-3, respectively. It reduces 5-aza-2-deoxycytidine-induced increases in MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, and MMP-14 expression as well as cell invasion in AsPC-1, BxPC-3, Hs766T, MiaPaCa2, and PANC-1 cancer cells. Topical administration of GM 1489 (100 μg) inhibits increases in ear thickness and epidermal hyperplasia induced by phorbol 12-myristate 13-acetate (TPA; Item No. ) and phorbol dibutyrate (PdiBu) in mice.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(3R)-3-
CAS Number
171347-75-4
Molecular Formula
C27H33N3O4
Formula Weight
463.6
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 50 mg/mL
- DMSO: 50 mg/mL
- Ethanol: 20 mg/mL
- PBS (pH 7.2): 0.2 mg/mL
λmax
222, 282 nm
SMILES
O=C([C@H](CC1=CNC2=C1C=CC=C2)NC([C@H](CC(C)C)CC(O)=O)=O)N[C@H](C3=CC=CC=C3)C
InChi Code
InChI=1S/C27H33N3O4/c1-17(2)13-20(15-25(31)32)26(33)30-24(14-21-16-28-23-12-8-7-11-22(21)23)27(34)29-18(3)19-9-5-4-6-10-19/h4-12,16-18,20,24,28H,13-15H2,1-3H3,(H,29,34)(H,30,33)(H,31,32)/t18-,20+,24-/m0/s1
InChi Key
BLPWNGOQQLJQOL-NRYAXDJKSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-24313-1 |
|---|---|
| Supplier Part Number | 24313-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 171347-75-4 |
| Energy Star | No |
| Green | No |
| Controlled | N |