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Cayman C6 NBD Sphingomyelin (d18:1/6:0)
List Price $502.00 Your Price $502.00
Cayman C6 NBD Sphingomyelin (d18:1/6:0) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-24328-1
MFG.PART: 24328-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
C6 NBD sphingomyelin is a biologically active derivative of sphingomyelin (Item Nos. | ) that is tagged with a fluorescent C6 nitrobenzoxadiazole (C6 NBD; Item No. ) group. C6 NBD sphingomyelin has been used to study the metabolism and transport of sphingomyelins., It is degraded in the plasma membrane to C6 NBD ceramide (Item No. ) by neutral sphingomyelinase, an enzyme with three-fold higher activity in undifferentiated HT29 cells than in differentiated cells. Unlike endogenous long-chain sphingomyelin and C6 sphingomyelin, C6 NBD sphingomyelin can be transported to the cell surface even in the presence of the vesicular transport inhibitor brefeldin A (Item No. ), but this transport can be blocked by multidrug resistance protein inhibitors in CHO Cells. This product is a mixture of the D-erythro and L-threo isomers of sphingomyelin. As this product is derived from a natural source, there may be variations in the sphingoid backbone. [Matreya, LLC. Catalog No. 1912]
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(7S)-4-hydrox
CAS Number
94885-04-8
Synonyms
- N-hexanoyl-NBD Sphingosylphosphorylcholine
- NBD SM(d18:1/6:0)
- NBD Sphingomyelin (d18:1/6:0)
Molecular Formula
C35H61N6O9P
Formula Weight
740.9
Purity
≥98%
Formulation
A solid
Solubility
- Chloroform: Soluble
- Ethanol: Soluble
- Methanol: Soluble
SMILES
O=C(CCCCCNC1=CC=C([N+]([O-])=O)C2=NON=C12)NC(COP(OCC[N+](C)(C)C)([O-])=O)C(O)/C=C/CCCCCCCCCCCCC
InChi Code
InChI=1S/C35H61N6O9P/c1-5-6-7-8-9-10-11-12-13-14-15-16-18-21-32(42)30(28-49-51(46,47)48-27-26-41(2,3)4)37-33(43)22-19-17-20-25-36-29-23-24-31(40(44)45)35-34(29)38-50-39-35/h18,21,23-24,30,32,42H,5-17,19-20,22,25-28H2,1-4H3,(H2-,36,37,39,43,46,47)/b21-18+
InChi Key
YDBDYTGWMRUUSN-DYTRJAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-24328-1 |
|---|---|
| Supplier Part Number | 24328-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 94885-04-8 |
| Energy Star | No |
| Green | No |
| Controlled | N |