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Cayman C6 D-threo Ceramide (d18:1/6:0)
List Price $256.00 Your Price $256.00
Cayman C6 D-threo Ceramide (d18:1/6:0) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-24389-1
MFG.PART: 24389-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
C6 D-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides., C6 D-threo Ceramide is cytotoxic to U937 cells in vitro (IC50 = 18 μM). It is metabolically inactive and, unlike C6 L-erythro ceramide (Item No. ), C6 D-threo ceramide cannot be converted to C6 glucosylceramide by ceramide glucosyltransferase. C6 D-threo Ceramide promotes survival of isolated rat spinal neurons when used at concentrations up to 2.5 μM but induces cell death at concentrations greater than 5 μM. It enhances IL-4 production induced by phorbol 12-myristate 13-acetate (PMA; Item No. ) in EL4 T cells when used at a concentration of 10 μM. [Matreya, LLC. Catalog No. 1809]
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[(1R,2R,3E)
CAS Number
189894-79-9
Synonyms
- N-hexanoyl-D-threo-Sphingosine
- D-threo Cer(d18:1/6:0)
- D-threo Ceramide (d18:1/6:0)
Molecular Formula
C24H47NO3
Formula Weight
397.6
Purity
≥98%
Formulation
A solid
SMILES
OC[C@H]([C@H](O)/C=C/CCCCCCCCCCCCC)NC(CCCCC)=O
InChi Code
InChI=1S/C24H47NO3/c1-3-5-7-8-9-10-11-12-13-14-15-16-18-19-23(27)22(21-26)25-24(28)20-17-6-4-2/h18-19,22-23,26-27H,3-17,20-21H2,1-2H3,(H,25,28)/b19-18+/t22-,23-/m1/s1
InChi Key
NPRJSFWNFTXXQC-KHZUJUORSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-24389-1 |
|---|---|
| Supplier Part Number | 24389-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 189894-79-9 |
| Energy Star | No |
| Green | No |
| Controlled | N |