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Cayman EOS (d18:1/30:0/18:2)
List Price $602.00 Your Price $602.00
Cayman EOS (d18:1/30:0/18:2) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-24394-1
MFG.PART: 24394-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
EOS is a ceramide found in the outer layer of the epidermis in mammals. It is comprised of an ω-hydroxy very long-chain ceramide (C28-36) esterified to the essential fatty acid linoleic acid (Item No. ). The consecutive regio- and stereospecific oxygenation of the linoleate portion of EOS by 12(R)-lipoxygenase (12(R)-LO) and eLOX3 is essential for the maintenance of the epidermal barrier to prevent water loss. Following oxygenation, the oxidized linoleate is hydrolyzed, leaving the ω-hydroxy end of the very long-chain fatty acid to covalently bind the protein layer, forming the corneocyte lipid envelope and sealing the gap between the extracellular lipid lamellae and the cornified cell envelope of the corneocyte. EOS (d18:1/30:0/18:2) is a sphingolipid that has been found in intact and desquamated human stratum corneum as well as porcine epidermis., [Matreya, LLC. Catalog No. 2084]
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
30-[[2-
CAS Number
97040-38-5
Synonyms
- N-(30-linoleoyloxy-triacontanoyl)-Sphingosine
- C48:2 EOS (d18:1/30:0w18:2 (9Z,12Z))
Molecular Formula
C66H125NO5
Formula Weight
1012.7
Purity
≥98%
Formulation
A solid
Solubility
- Chloroform: soluble
- DMF: soluble
- Methanol: soluble
SMILES
OCC(NC(CCCCCCCCCCCCCCCCCCCCCCCCCCCCCOC(CCCCCCC/C=C\C/C=C\CCCCC)=O)=O)C(O)/C=C/CCCCCCCCCCCCC
InChi Code
InChI=1S/C66H125NO5/c1-3-5-7-9-11-13-15-17-31-36-40-44-48-52-56-60-66(71)72-61-57-53-49-45-41-37-33-30-28-26-24-22-20-18-19-21-23-25-27-29-32-35-39-43-47-51-55-59-65(70)67-63(62-68)64(69)58-54-50-46-42-38-34-16-14-12-10-8-6-4-2/h11,13,17,31,54,58,63-64,68-69H,3-10,12,14-16,18-30,32-53,55-57,59-62H2,1-2H3,(H,67,70)/b13-11-,31-17-,58-54+
InChi Key
CJKGLEVYDCRGBX-UUHZUQCYSA-N
Origin
Synthetic
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-24394-1 |
|---|---|
| Supplier Part Number | 24394-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 97040-38-5 |
| Energy Star | No |
| Green | No |
| Controlled | N |