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Cayman EOS-d9 (d18:1-d9/32:0/18:2)
List Price $736.00 Your Price $736.00
Cayman EOS-d9 (d18:1-d9/32:0/18:2) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-24423-1
MFG.PART: 24423-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
EOS-d9 (d18:1-d9/32:0/18:2) is intended for use as an internal standard for the quantification of EOS (Item No. ) by GC- or LC-MS. EOS is a ceramide found in the outer layer of the epidermis in mammals. It is comprised of an ω-hydroxy very long-chain fatty acid (C28-36) esterified to the essential fatty acid linoleic acid (Item No. ) and glucosylated to sphingosine. The consecutive regio- and stereospecific oxygenation of the linoleate portion of EOS by 12(R)-lipoxygenase (12(R)-LO) and eLOX3 is essential for the maintenance of the epidermal barrier to prevent water loss. Following oxygenation, the oxidized linoleate is hydrolyzed, leaving the ω-hydroxy end of the very long-chain fatty acid to covalently bind the protein layer, forming the corneocyte lipid envelope and sealing the gap between the extracellular lipid lamellae and the cornified cell envelope of the corneocyte. [Matreya, LLC. Catalog No. 2208]
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(9Z,12Z)-9,12-
CAS Number
2692624-26-1
Synonyms
- N-(32-linoleoyloxy-dotriacontanoyl)-Sphingosine-d9
Molecular Formula
C68H120D9NO5
Formula Weight
1049.8
Purity
≥99% deuterated forms (d1-d9)
Formulation
A solid
Solubility
- Chloroform: soluble
- DMF: soluble
- Methanol: soluble
SMILES
OC[C@H](NC(CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCOC(CCCCCCC/C=C\C/C=C\CCCCC)=O)=O)[C@H](O)/C=C/CCCCCCCCCC([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H]
InChi Code
InChI=1S/C68H129NO5/c1-3-5-7-9-11-13-15-17-33-38-42-46-50-54-58-62-68(73)74-63-59-55-51-47-43-39-35-32-30-28-26-24-22-20-18-19-21-23-25-27-29-31-34-37-41-45-49-53-57-61-67(72)69-65(64-70)66(71)60-56-52-48-44-40-36-16-14-12-10-8-6-4-2/h11,13,17,33,56,60,65-66,70-71H,3-10,12,14-16,18-32,34-55,57-59,61-64H2,1-2H3,(H,69,72)/b13-11-,33-17-,60-56+/t65-,66+/m0/s1/i2D3,4D2,6D2,8D2
InChi Key
NKZDGPMKCOVGRH-SIBFFXIQSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-24423-1 |
|---|---|
| Supplier Part Number | 24423-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 2692624-26-1 |
| Energy Star | No |
| Green | No |
| Controlled | N |