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Cayman Neurokinin B (trifluoroacetate salt)
List Price $120.00 Your Price $120.00
Cayman Neurokinin B (trifluoroacetate salt) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-24542-1
MFG.PART: 24542-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Neurokinin B is a tachykinin peptide agonist of the neurokinin-3 receptor (NK3; Ki = 0.8 nM)., In vitro, neurokinin B dose-dependently induces calcium mobilization in HEK293 cells expressing NK3 (EC50 = 0.5 nM), an effect inhibited by NK3 antagonists. Neurokinin B potentiates electrically-induced contractions in rat vas deferens and increases vasodilation in rat hind paw in a dose-dependent manner. In juvenile male rhesus monkeys, neurokinin B (100 µg, i.v.) stimulates luteinizing hormone (LH) release and acts within the hypothalamus, suggesting a role in initiating puberty.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
L-α-aspartyl-
Synonyms
- Neurokinin β
- Neuromedin K
Molecular Formula
C55H79N13O14S2 • XCF3COOH
Formula Weight
1210.4
Purity
≥95%
Formulation
A lyophilized powder
Solubility
- Formic Acid: 1 mg/mL
SMILES
O=C(N[C@H](C(N[C@@H](CC1=CC=CC=C1)C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N)=O)CCSC)=O)CC(C)C)=O)=O)C(C)C)=O)CC2=CC=CC=C2)=O)=O)CC(O)=O)[C@@H](NC([C@@H](NC([C@H](CC(O)=O)N)=O)CCSC)=O)CC3=CNC=N3.OC(C(F)(F)F)=O
InChi Code
InChI=1S/C55H79N13O14S2.C2HF3O2/c1-30(2)21-38(50(77)62-36(47(57)74)17-19-83-5)61-43(69)28-59-55(82)46(31(3)4)68-54(81)40(23-33-15-11-8-12-16-33)65-51(78)39(22-32-13-9-7-10-14-32)64-53(80)42(26-45(72)73)67-52(79)41(24-34-27-58-29-60-34)66-49(76)37(18-20-84-6)63-48(75)35(56)25-44(70)71;3-2(4,5)1(6)7/h7-16,27,29-31,35-42,46H,17-26,28,56H2,1-6H3,(H2,57,74)(H,58,60)(H,59,82)(H,61,69)(H,62,77)(H,63,75)(H,64,80)(H,65,78)(H,66,76)(H,67,79)(H,68,81)(H,70,71)(H,72,73);(H,6,7)/t35-,36-,37-,38-,39-,40-,41-,42-,46-;/m0./s1
InChi Key
ZQXWSRCHLZXNEZ-SBPCDBINSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-24542-1 |
|---|---|
| Supplier Part Number | 24542-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |