Cayman Mca-YVADAP-K(Dnp)-OH (trifluoroacetate salt)

Name: Cayman Mca-YVADAP-K(Dnp)-OH (trifluoroacetate salt)
SKU: CAYM-24562-500
Price: 174.00 USD

List Price $174.00 Your Price $174.00

Cayman Mca-YVADAP-K(Dnp)-OH (trifluoroacetate salt) - CAYM (Additional S&H Or Hazmat Fees May Apply)

NETA PART: CAYM-24562-500

MFG.PART: 24562-500

UNSPSC: 12352200

Manufacturer: Cayman

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Description

Product Description

Mca-YVADAP-K(Dnp)-OH is a substrate for caspase-1 and angiotensin-converting enzyme 2 (ACE2).^, Upon cleavage by caspase-1 or ACE2, 7-methoxycoumarin-4-acetyl (Mca) is released and its fluorescence can be used to quantify enzyme activity. Mca displays excitation/emission maxima of 328/420 nm, respectively.

WARNING This product is not for human or veterinary use.

Technical Information

Formal Name

N-[2-(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-tyrosyl-L-valyl-L-alanyl-L-α-aspartyl-L-alanyl-L-prolyl-N⁶-(2,4-dinitrophenyl)-L-lysine, trifluoroacetate salt

Synonyms

Caspase-1 Fluorogenic Substrate V
Mca-Tyr-Val-Ala-Asp-Ala-Pro-Lys(DNP)-OH
Mca-YVADAP-Lys(Dnp)-OH
(7-Methoxycoumarin-4-yl)acetyl-YVADAPK(2,4-dinitrophenyl)-OH

Molecular Formula

C₅₃H₆₄N₁₀O₁₉ • XCF₃COOH

Formula Weight

1145.1

Purity

≥95%

Formulation

A lyophilized powder

Solubility

Water: 1 mg/mL

SMILES

COC1=CC=C(C(CC(N[C@@H](CC2=CC=C(O)C=C2)C(N[C@@H](C(C)C)C(N[C@@H](C)C(N[C@@H](CC(O)=O)C(N[C@@H](C)C(N3CCC[C@H]3C(N[C@@H](CCCCNC4=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C4)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=CC(O5)=O)C5=C1.OC(C(F)(F)F)=O

InChi Code

InChI=1S/C53H64N10O19.C2HF3O2/c1-27(2)46(60-49(71)38(21-30-11-14-33(64)15-12-30)57-43(65)22-31-23-45(68)82-42-25-34(81-5)16-17-35(31)42)51(73)55-28(3)47(69)59-39(26-44(66)67)48(70)56-29(4)52(74)61-20-8-10-40(61)50(72)58-37(53(75)76)9-6-7-19-54-36-18-13-32(62(77)78)24-41(36)63(79)80;3-2(4,5)1(6)7/h11-18,23-25,27-29,37-40,46,54,64H,6-10,19-22,26H2,1-5H3,(H,55,73)(H,56,70)(H,57,65)(H,58,72)(H,59,69)(H,60,71)(H,66,67)(H,75,76);(H,6,7)/t28-,29-,37-,38-,39-,40-,46-;/m0./s1

InChi Key

IDHHNDRKPWTJSE-VXJHEXFUSA-N

Shipping & Storage Information

Storage

-20°C

Shipping

Room Temperature in continental US; may vary elsewhere

Stability

≥ 4 years

Specifications

More Information
SKU	CAYM-24562-500
Supplier Part Number	24562-500
UM	EA
UNSPSC	12352200
Manufacturer	Cayman
MSDS URL	Click here
Temperature	-20
Refrigerated-Frozen	Y
CountryOfOrigin	United States
ProductLine	CAYM
Qty	1
MinOrderQty	1
Weight	7.000000
Lead Time	5
Hazardous	N
Energy Star	No
Green	No
Controlled	N

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Cayman Mca-YVADAP-K(Dnp)-OH (trifluoroacetate salt)

Product Description

Technical Information

Shipping & Storage Information

Product Title