Cayman Benzomalvin A

Benzomalvin A is a fungal metabolite produced by Penicillium.^, It inhibits yeast α-glucosidase in vitro (IC₅₀ = 383.2 μM). In vivo, benzomalvin A (3.1-31.6 mg/kg) decreases plasma glucose levels in mice following administration of sucrose. It also decreases the plasma glucose postprandial peak in nicotinamide-streptozotocin-induced hyperglycemic mice when administered at a dose of 10 mg/kg. Benzomalvin A also acts as an antagonist of neurokinin-1 (NK₁) receptors, inhibiting binding of substance P (Item No. ) to guinea pig, rat, and human NK₁ (K_is = 12, 42, and 43 μM, respectively).

WARNING This product is not for human or veterinary use.