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Cayman Dehydroevodiamine (hydrochloride)
List Price $171.00 Your Price $171.00
Cayman Dehydroevodiamine (hydrochloride) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-25101-100
MFG.PART: 25101-100
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Dehydroevodiamine is an alkaloid that has been isolated from E. rutaecarpa and has anti-inflammatory, antiarrhythmic, hypotensive, and anti-amnesic biological activities.,,, It inhibits LPS-induced secretion of prostaglandin E2 (PGE2; Item No. ) in RAW 264.7 mouse macrophages when used at a concentration of 30 μM. Dehydroevodiamine (0.1-0.3 μM) reduces the upstroke velocity, action potential amplitude, and contractile force of electrically-stimulated primary human atrial trabeculae. In vivo, dehydroevodiamine (10 mg/kg) decreases mean arterial blood pressure (MAP) by approximately 30% in rats. Dehydroevodiamine (1.5 mg/kg) also inhibits amnesia induced by amyloid-β (25-35) (Item No. ) and increases latency to step-through in a passive avoidance test in mice.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
8,14-dihydro-
CAS Number
111664-82-5
Molecular Formula
C19H15N3O • HCl
Formula Weight
337.8
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 2.5 mg/mL
- DMSO: 12.5 mg/mL
- Ethanol: 2.5 mg/mL
λmax
248, 315, 367 nm
SMILES
CN(C1=CC=CC=C1C(N2CC3)=O)C2=C4C3=C(C=CC=C5)C5=N4.Cl
InChi Code
InChI=1S/C19H15N3O.ClH/c1-21-16-9-5-3-7-14(16)19(23)22-11-10-13-12-6-2-4-8-15(12)20-17(13)18(21)22;/h2-9H,10-11H2,1H3;1H
InChi Key
SVOMSEHNGXLQRU-UHFFFAOYSA-N
Origin
Plant/Euodiae fructus
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-25101-100 |
|---|---|
| Supplier Part Number | 25101-100 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 111664-82-5 |
| Energy Star | No |
| Green | No |
| Controlled | N |