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Cayman Seneciphylline
List Price $41.00 Your Price $41.00
Cayman Seneciphylline - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-25146-1
MFG.PART: 25146-1
UNSPSC: 12352200
Manufacturer: Cayman


Product Description
Seneciphylline is an alkaloid that has been found F. japonicum and has diverse biological activites.,,, It induces autophagy and decreases viability of Huh7.5 cells in a concentration-dependent manner. Seneciphylline is also cytotoxic to HepG2 cells (IC20 = 0.66 mm). Dietary administration of seneciphylline induces sex-linked recessive lethality in male Drosophila. Seneciphylline (80 mg/kg) increases the activity of epoxide hydrase and glutathione-S-transferase and decreases activity of cytochrome P450 and aminopyrine demethylase in rat liver.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(3Z,6R,14aR, 14bR)-3-ethyl idene-3,4,5, 6,9,11,13,14, 14a,14b-deca hydro-6- hydroxy-6- methyl-5- methylene- [1,6]dioxa cyclododecino [2,3,4-gh] pyrrolizine- 2,7-dione
CAS Number
480-81-9
Synonyms
- NSC 30622
Molecular Formula
C18H23NO5
Formula Weight
333.4
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 5 mg/mL
- DMSO: 2 mg/mL
- Ethanol: 1 mg/mL
- PBS (pH 7.2): 0.1 mg/mL
λmax
212 nm
SMILES
O=C(/C(CC([C@@]1(C)O)=C)=C\C)O[C@]2([H])CCN3[C@]2([H])C(COC1=O)=CC3
InChi Code
InChI=1S/C18H23NO5/c1-4-12-9-11(2)18(3,22)17(21)23-10-13-5-7-19-8-6-14(15(13)19)24-16(12)20/h4-5,14-15,22H,2,6-10H2,1,3H3/b12-4-/t14-,15-,18-/m1/s1
InChi Key
FCEVNJIUIMLVML-QPSVUOIXSA-N
Origin
Plant/Senecio scandens Buch.-Ham.
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-25146-1 |
|---|---|
| Supplier Part Number | 25146-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 480-81-9 |
| Energy Star | No |
| Green | No |
| Controlled | N |

