Cayman Procyanidin C1

Procyanidin C1 is a polyphenol flavonoid trimer of (–)-epicatechin (Item No. ) that has HIV-related and antioxidant activities.^, It activates latent HIV-1 provirus in JLR2 cells when used at concentrations ranging from 12.5 to 50 µM and increases NF-κB-dependent transcriptional activity in Jurkat T cells. Procyanidin C1 also scavenges 2,2’-diphenyl-1-picrylhydrazyl (DPPH) radicals (IC₅₀ = 3.2 µg/mL) and inhibits the activity of α-glucosidase (IC₅₀ = 3.8 µg/mL) and 15-lipoxygenase (15-LO; IC₅₀ = 57.6 µg/mL). Procyanidin C1 (10 µg/mL) prevents phosphorylation of ERK1/2 and the production of reactive oxygen species (ROS) in THP-1 cells.

WARNING This product is not for human or veterinary use.