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Cayman SGC3027
List Price
$68.00
Your Price
$68.00
Cayman SGC3027 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-25325-1
MFG.PART:
25325-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
SGC3027 is a prodrug form of the protein arginine methyltransferase 7 (PRMT7) inhibitor SGC8158. It is converted by intracellular reductases to SGC8158, which inhibits PRMT7 with an IC50 value of less than 2.5 nM for inhibition of histone H2B (23-37) methylation. SGC3027 inhibits methylation of heat shock protein 70 (Hsp70) in vitro (IC50 = 2.4 µM). See the website for more information.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-(4- ((((2S,3S,4R, 5R)-5-(6- amino-9H- purin-9-yl)- 3,4-dihydroxy tetrahydro furan-2-yl) methyl)thio) butyl)-N- ((4-chloro- [1,1- biphenyl]-3- yl)methyl)-3- methyl-3- (2,4,5- trimethyl- 3,6-dioxo cyclohexa- 1,4-dien-1- yl)butanamide
CAS Number
2624313-13-7
Molecular Formula
C41H47ClN6O6S
Formula Weight
787.4
Purity
≥98%
Formulation
A solid
Solubility
- DMSO: soluble
SMILES
ClC1=CC=C(C2=CC(CN(C(CC(C)(C)C3=C(C)C(C(C)=C(C)C3=O)=O)=O)CCCCSC[C@@H]4[C@@H](O)[C@@H](O)[C@H](N5C(N=CN=C6N)=C6N=C5)O4)=CC=C2)C=C1
InChi Code
InChI=1S/C41H47ClN6O6S/c1-23-24(2)35(51)32(25(3)34(23)50)41(4,5)18-31(49)47(19-26-9-8-10-28(17-26)27-11-13-29(42)14-12-27)15-6-7-16-55-20-30-36(52)37(53)40(54-30)48-22-46-33-38(43)44-21-45-39(33)48/h8-14,17,21-22,30,36-37,40,52-53H,6-7,15-16,18-20H2,1-5H3,(H2,43,44,45)/t30-,36-,37-,40-/m1/s1
InChi Key
MLJVGAYSVYMPSB-MSUKGTQXSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-25325-1 |
|---|---|
| Supplier Part Number | 25325-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 2624313-13-7 |
| Energy Star | No |
| Green | No |
| Controlled | N |