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Cayman ITE
List Price
$107.00
Your Price
$107.00
Cayman ITE - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-25355-10
MFG.PART:
25355-10
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
ITE is an endogenous aryl hydrocarbon receptor (AhR) agonist. It binds to AhR (Kd = 65 nM) and induces AhR-dependent transcription in luciferase reporter assays when used at a concentration of 0.01 µM. ITE (1 µM) inhibits anti-CD40- and IL-4-induced differentiation of isolated mouse splenic B cells, as well as proliferation and migration of SKOV3 ovarian cancer cells., In vivo, ITE (200 µg/animal, i.p.) reduces retinal detachment and ocular inflammatory cell infiltration in a mouse model of experimental autoimmune uveitis induced by complete Freunds adjuvant (CFA) and M. tuberculosis. ITE (80 mg/kg, i.p.) reduces tumor growth by 39% in an OVCAR-3 mouse xenograft model.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-(1H-indol-
CAS Number
448906-42-1
Molecular Formula
C14H10N2O3S
Formula Weight
286.3
Purity
≥98%
Formulation
A solid
Solubility
- DMF: 20 mg/mL
- DMF:PBS (pH 7.2) (1:6): 0.14 mg/mL
- DMSO: 10 mg/mL
λmax
211, 273, 279, 356 nm
SMILES
O=C(C1=NC(C(OC)=O)=CS1)C2=CNC3=CC=CC=C32
InChi Code
InChI=1S/C14H10N2O3S/c1-19-14(18)11-7-20-13(16-11)12(17)9-6-15-10-5-3-2-4-8(9)10/h2-7,15H,1H3
InChi Key
KDDXOGDIPZSCTM-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-25355-10 |
|---|---|
| Supplier Part Number | 25355-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 448906-42-1 |
| Energy Star | No |
| Green | No |
| Controlled | N |