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Cayman IMP-1088
List Price $132.00 Your Price $132.00
Cayman IMP-1088 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-25366-1
MFG.PART: 25366-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
IMP-1088 is an inhibitor of N-myristoyltransferase 1 (NMT1) and NMT2 (IC50 = <1 nM for both human enzymes). It inhibits replication of rhinovirus (RV), the virus most commonly responsible for the common cold, by inhibiting myristoylation of the RV capsid protein VP0 from strain RV-A16 in HeLa cells. IMP-1088 (500 nM) reduces RV-A16, RV-A1, RV-B14, and RV-A28 viral titers in HeLa cells without affecting cell growth (IC50 = >1,000 nM). It also blocks production of infectious RV-16 virus in primary human bronchial epithelial cells (hBECs) when added 3 hours post infection via inhibition of viral capsid assembly.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5-[3,4-
CAS Number
2059148-82-0
Molecular Formula
C25H29F2N5O
Formula Weight
453.5
Purity
≥95%
Formulation
A solution in methyl acetate
Solubility
- Methyl Acetate: 10 mg/mL
λmax
217, 244, 305 nm
SMILES
FC1=C(F)C=CC(C2=CC=C(N(C)N=C3CN(C)C)C3=C2)=C1OCCC4=C(C)N(C)N=C4C
InChi Code
InChI=1S/C25H29F2N5O/c1-15-18(16(2)31(5)28-15)11-12-33-25-19(8-9-21(26)24(25)27)17-7-10-23-20(13-17)22(14-30(3)4)29-32(23)6/h7-10,13H,11-12,14H2,1-6H3
InChi Key
SOXNKJCQBRQUMS-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-25366-1 |
|---|---|
| Supplier Part Number | 25366-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 2059148-82-0 |
| Energy Star | No |
| Green | No |
| Controlled | N |