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Cayman BB-F-Yne
List Price
$193.00
Your Price
$193.00
Cayman BB-F-Yne - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-25379-1
MFG.PART:
25379-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
BB-F-Yne is a cell-permeable derivative of the protein arginine deiminase (PAD) inhibitor BB-Cl-amidine (Item No. ) that contains an alkyne moiety for use in click chemistry reactions. BB-F-Yne inhibits PAD1-4 with kinact/KI values of 900, 1,200, 3,400, and 3,750 M-1min-1, respectively. It has been used for labeling PADs in cell-free and cell-based assays, followed by click reactions with azide-modified TAMRA reporters or biotin capture reagents.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[(1S)-1- (1H- benzimidazol- 2-yl)-4-[(2- fluoro-1- iminoethyl) amino]butyl]- 4-ethynyl- [1,1- biphenyl]-4- carboxamide
CAS Number
2219331-30-1
Synonyms
- Click Tag™ BB-F-Yne
Molecular Formula
C28H26FN5O
Formula Weight
467.5
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 5 mg/mL
- DMF:PBS (pH 7.2) (1:5): 0.16 mg/mL
- DMSO: 20 mg/mL
λmax
284 nm
SMILES
O=C(N[C@@H](CCCNC(CF)=N)C1=NC2=C(C=CC=C2)N1)C(C=C3)=CC=C3C4=CC=C(C#C)C=C4
InChi Code
InChI=1S/C28H26FN5O/c1-2-19-9-11-20(12-10-19)21-13-15-22(16-14-21)28(35)34-25(8-5-17-31-26(30)18-29)27-32-23-6-3-4-7-24(23)33-27/h1,3-4,6-7,9-16,25H,5,8,17-18H2,(H2,30,31)(H,32,33)(H,34,35)/t25-/m0/s1
InChi Key
AVWXDAJEHXZGSV-VWLOTQADSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-25379-1 |
|---|---|
| Supplier Part Number | 25379-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 2219331-30-1 |
| Energy Star | No |
| Green | No |
| Controlled | N |