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Cayman 5α,6α-epoxy Cholestanol
List Price $75.00 Your Price $75.00
Cayman 5α,6α-epoxy Cholestanol - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-25539-50
MFG.PART: 25539-50
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
5α,6α-epoxy Cholestanol is an oxysterol and a metabolite of cholesterol produced by oxidation.1 5α,6α-epoxy Cholestanol accumulates in MCF-7 breast cancer cells in a reactive oxygen species-dependent manner following tamoxifen and PBPE application and induces triacylglycerol biosynthesis by binding to liver x receptor β (LXRβ).2 5α,6α-epoxy Cholestanol levels are increased in rat aorta and mesenteric artery following orchidectomy, an effect that can be prevented by a DHA-supplemented diet.1 Levels are also increased in post-mortem frontal and occipital cortex of patients with Alzheimer’s disease.3
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(3β,5α,6α)-
CAS Number
1250-95-9
Synonyms
- Cholesterol 5α,6α-epoxide
- 5α,6α-Epoxycholesterol
- NSC 18176
Molecular Formula
C27H46O2
Formula Weight
402.7
Purity
≥95%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 2 mg/mL
- DMSO: 0.1 mg/mL
- Ethanol: 20 mg/mL
- Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/mL
SMILES
C[C@H](CCCC(C)C)[C@@]1([H])CC[C@@]2([H])[C@]3([H])C[C@H]4[C@@]5(O4)C[C@@H](O)CC[C@]5(C)[C@@]3([H])CC[C@@]21C
InChi Code
InChI=1S/C27H46O2/c1-17(2)7-6-8-18(3)21-9-10-22-20-15-24-27(29-24)16-19(28)11-14-26(27,5)23(20)12-13-25(21,22)4/h17-24,28H,6-16H2,1-5H3/t18-,19+,20+,21-,22+,23+,24+,25-,26-,27+/m1/s1
InChi Key
PRYIJAGAEJZDBO-ZEQHCUNVSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-25539-50 |
|---|---|
| Supplier Part Number | 25539-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1250-95-9 |
| Energy Star | No |
| Green | No |
| Controlled | N |