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Cayman RK-20448
List Price $93.00 Your Price $93.00
Cayman RK-20448 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-25606-1
MFG.PART: 25606-1
UNSPSC: 12352200
Manufacturer: Cayman


Product Description
RK-20448 is an ATP-competitive inhibitor of Lck, Src, KDR/VEGF2R, and Tie-2 (IC50s = 0.24, 1.19, 10.74, and 5.85 µM, respectively). It also inhibits BLK, Csk, Fyn, and Lyn (IC50s = 0.37, 4.27, 2.03, and 0.43 µM, respectively). RK-20448 is the cis isomer of A-419259 (Item No. ).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
7-[cis-4-(4- methyl-1- piperazinyl) cyclohexyl]- 5-(4-phenoxy phenyl)-7H- pyrrolo[2,3- d]pyrimidin- 4-amine
CAS Number
479501-40-1
Molecular Formula
C29H34N6O
Formula Weight
482.6
Purity
≥98%
Formulation
A solid
Solubility
- DMSO: 10 mm
SMILES
NC1=C(C(C2=CC=C(OC3=CC=CC=C3)C=C2)=CN4[C@H]5CC[C@@H](N6CCN(C)CC6)CC5)C4=NC=N1
InChi Code
InChI=1S/C29H34N6O/c1-33-15-17-34(18-16-33)22-9-11-23(12-10-22)35-19-26(27-28(30)31-20-32-29(27)35)21-7-13-25(14-8-21)36-24-5-3-2-4-6-24/h2-8,13-14,19-20,22-23H,9-12,15-18H2,1H3,(H2,30,31,32)/t22-,23+
InChi Key
FDVSOQRNTAPCHB-ZRZAMGCNSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-25606-1 |
|---|---|
| Supplier Part Number | 25606-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | Australia |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 479501-40-1 |
| Energy Star | No |
| Green | No |
| Controlled | N |

