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Cayman MK-0941
List Price $41.00 Your Price $41.00
Cayman MK-0941 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-25642-1
MFG.PART: 25642-1
UNSPSC: 12352200
Manufacturer: Cayman


Product Description
MK-0941 is a glucokinase activator with EC50 values of 0.24 and 0.065 µM at low (2.5 mm) and high (10 mm) concentrations of glucose, respectively. It increases insulin secretion from isolated rat islets of Langerhans and glucose uptake by hepatocytes in vitro. MK-0941 reduces blood glucose levels in high-fat diet-fed db/db mice and in high-fat diet-fed mice with diabetes induced by streptozotocin (Item No. ).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
3-[[6-(ethyl sulfonyl)-3- pyridinyl] oxy]-5-[(1S)- 2-hydroxy-1- methylethoxy]- N-(1-methyl- 1H-pyrazol-3- yl)-benz amide, monomethane sulfonate
CAS Number
1137916-97-2
Molecular Formula
C21H24N4O6S • CH3SO3H
Formula Weight
556.6
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 20 mg/mL
- DMSO: 20 mg/mL
- Ethanol: 5 mg/mL
λmax
214, 276 nm
SMILES
CCS(C1=CC=C(OC2=CC(O[C@@H](C)CO)=CC(C(NC3=NN(C)C=C3)=O)=C2)C=N1)(=O)=O.O=S(O)(C)=O
InChi Code
InChI=1S/C21H24N4O6S.CH4O3S/c1-4-32(28,29)20-6-5-16(12-22-20)31-18-10-15(9-17(11-18)30-14(2)13-26)21(27)23-19-7-8-25(3)24-19;1-5(2,3)4/h5-12,14,26H,4,13H2,1-3H3,(H,23,24,27);1H3,(H,2,3,4)/t14-;/m0./s1
InChi Key
PIDNRTWDGDJKSQ-UQKRIMTDSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-25642-1 |
|---|---|
| Supplier Part Number | 25642-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1137916-97-2 |
| Energy Star | No |
| Green | No |
| Controlled | N |

