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Cayman Ivabradine-d3 (hydrochloride)
List Price
$445.00
Your Price
$445.00
Cayman Ivabradine-d3 (hydrochloride) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-25711-1
MFG.PART:
25711-1
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
Ivabradine-d3 is intended for use as an internal standard for the quantification of ivabradine (Item No. ) by GC- or LC-MS. Ivabradine is a hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blocker that blocks the mixed sodium/potassium inward funny current (If) in HEK293 cells expressing mouse HCN1, human HCN2, and human HCN4 (EC50s = 4.5, 4.52, and 4.28 μM, respectively). In vivo, ivabradine (10 mg/kg per day) reduces heart rate, incidence of ventricular tachycardia and ventricular fibrillation, and arrhythmic mortality in a rat model of myocardial infarction. Formulations containing ivabradine have been used in the treatment of heart failure and angina.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(S)-3-(3-
CAS Number
1217809-61-4
Molecular Formula
C27H33D3N2O5 • HCl
Formula Weight
508.1
Purity
≥99% deuterated forms (d1-d3)
Formulation
A solid
Solubility
- DMSO: Slightly Soluble
- Methanol: Slightly Soluble
SMILES
COC(C(OC)=C1)=CC2=C1[C@H](C2)CN(C([2H])([2H])[2H])CCCN3CCC(C=C(OC)C(OC)=C4)=C4CC3=O.Cl
InChi Code
InChI=1S/C27H36N2O5.ClH/c1-28(17-21-11-20-14-25(33-4)26(34-5)16-22(20)21)8-6-9-29-10-7-18-12-23(31-2)24(32-3)13-19(18)15-27(29)30;/h12-14,16,21H,6-11,15,17H2,1-5H3;1H/t21-;/m1./s1/i1D3;
InChi Key
HLUKNZUABFFNQS-AFMQDYKRSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-25711-1 |
|---|---|
| Supplier Part Number | 25711-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | Canada |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 1217809-61-4 |
| Energy Star | No |
| Green | No |
| Controlled | N |