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Cayman Despropionyl Para-Methylfentanyl; Purity- Greater Than Or
List Price
$356.00
Your Price
$356.00
Cayman Despropionyl Para-Methylfentanyl; Purity- Greater Than Or Equal To 98%; Size- 5 Mg; - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-25745-5
MFG.PART:
25745-5
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
M2I-1 is an inhibitor of the protein-protein interaction between the spindle assembly checkpoint protein mitotic arrest deficient 2 (Mad2) and cell division cycle 20 (Cdc20), a coactivator of the anaphase-promoting complex/cyclosome (APC/C). It inhibits Mad2 binding to Cdc20111-138 when used at concentrations ranging from 6.25 to 100 μM. M2I-1 (25 μM) reduces increases in mitotic duration induced by paclitaxel (Item No. ) in HeLa cells. M2I-1 (20-120 μM) reduces 4-cell embryo and blastocyst formation in hydrogen peroxide-exposed mouse zygotes, as well as increases the rate of sex chromosome mosaicism in male mouse in vitro fertilization-derived embryos.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
5-[[4-[bis(2- methylpropyl) amino]-3-nitro phenyl]methylene] dihydro-2-thioxo- 4,6(1H,5H)- pyrimidinedione
CAS Number
312271-03-7
Synonyms
- Mad2 Inhibitor-1
Molecular Formula
C19H24N4O4S
Formula Weight
404.5
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 25 mg/ml
- DMSO: 25 mg/ml
- Ethanol: slightly soluble
λmax
229, 247, 272, 467 nm
SMILES
S=C1NC(/C(C(N1)=O)=C/C2=CC=C(N(CC(C)C)CC(C)C)C([N+]([O-])=O)=C2)=O
InChi Code
InChI=1S/C19H24N4O4S/c1-11(2)9-22(10-12(3)4)15-6-5-13(8-16(15)23(26)27)7-14-17(24)20-19(28)21-18(14)25/h5-8,11-12H,9-10H2,1-4H3,(H2,20,21,24,25,28)
InChi Key
BWEKPQUKWLNUKX-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-25745-5 |
|---|---|
| Featured | No |
| Supplier Part Number | 25745-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Refrigerated |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 2 |
| Hazardous | N |
| CAS Number | 28456-20-4 |
| Energy Star | No |
| Green | No |
| ACT Ecolabel | No |
| Controlled | N |