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Cayman Trilobatin
List Price $73.00 Your Price $73.00
Cayman Trilobatin - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-25837-1
MFG.PART: 25837-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Trilobatin is a dihydrochalcone glucoside and derivative of phloretin (Item No. ) that has been found in Rooibos (A. linearis) tea and has diverse biological activities.,,,, It reduces survival of Bel 7402 and HepG2 cancer cells when used at a concentration of 100 μM. Trilobatin increases superoxide dismutase (SOD) and glutathione peroxidase (GPX) activity (EC50s = 129 and 128 μM, respectively) and inhibits lipid peroxidation (IC50 = 88 μM) in rat liver homogenates. Pretreatment with trilobatin reduces hydrogen peroxide-induced cell death and production of mitochondrial reactive oxygen species (ROS), prevents reduction in the mitochondrial membrane potential, and increases the activity of GPX, SOD2, and isocitrate dehydrogenase 2 (IDH2) in PC12 neuronal cells. Trilobatin inhibits infection by various HIV-1 strains (IC50s = 2.91-27.11 μM) without inducing cytotoxicity in target cells.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
1-[4-(β-D-
CAS Number
4192-90-9
Synonyms
- Phloretin-4-O-glucoside
Molecular Formula
C21H24O10
Formula Weight
436.4
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMF: 20 mg/mL
- DMSO: 25 mg/mL
- Ethanol: 20 mg/mL
- PBS (pH 7.2): 0.1 mg/mL
λmax
225, 283 nm
SMILES
OC1=CC=C(CCC(C2=C(O)C=C(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)C=C2O)=O)C=C1
InChi Code
InChI=1S/C21H24O10/c22-9-16-18(27)19(28)20(29)21(31-16)30-12-7-14(25)17(15(26)8-12)13(24)6-3-10-1-4-11(23)5-2-10/h1-2,4-5,7-8,16,18-23,25-29H,3,6,9H2/t16-,18-,19+,20-,21-/m1/s1
InChi Key
GSTCPEBQYSOEHV-QNDFHXLGSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-25837-1 |
|---|---|
| Supplier Part Number | 25837-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 4192-90-9 |
| Energy Star | No |
| Green | No |
| Controlled | N |