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Cayman H-151
List Price $591.00 Your Price $591.00
Cayman H-151 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-25857-50
MFG.PART: 25857-50
UNSPSC: 12352200
Manufacturer: Cayman


Product Description
H-151 is an inhibitor of stimulator of interferon genes (STING).1 It forms an adduct with mouse STING in serum and acts in an irreversible manner. It inhibits the type I interferon (IFN) response and reduces the phosphorylation of TBK1 and palmitoylation of human STING (hsSTING) in vitro. It also reduces increases in mouse serum levels of IFN-β and IL-6 induced by the STING agonist 10-carboxymethyl-9-acridanone (CMA).
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-(4-ethyl phenyl)-N- 1H-indol-3- yl-urea
CAS Number
941987-60-6
Molecular Formula
C17H17N3O
Formula Weight
279.3
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 30 mg/mL
- DMSO: 30 mg/mL
- DMSO:PBS (pH 7.2) (1:2): 0.3 mg/mL
- Ethanol: 10 mg/mL
λmax
236, 258 nm
SMILES
CCC1=CC=C(NC(NC2=CNC3=C2C=CC=C3)=O)C=C1
InChi Code
InChI=1S/C17H17N3O/c1-2-12-7-9-13(10-8-12)19-17(21)20-16-11-18-15-6-4-3-5-14(15)16/h3-11,18H,2H2,1H3,(H2,19,20,21)
InChi Key
UJZDIKVQFMCLBE-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 2 years
| SKU | CAYM-25857-50 |
|---|---|
| Supplier Part Number | 25857-50 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 941987-60-6 |
| Energy Star | No |
| Green | No |
| Controlled | N |

