We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn about our cookie policy.
Cayman APC 366 (trifluoroacetate salt)
List Price $41.00 Your Price $41.00
Cayman APC 366 (trifluoroacetate salt) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-25990-1
MFG.PART: 25990-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
APC 366 is a mast cell tryptase inhibitor (Ki = 7.1 μM for human recombinant enzyme). It reduces maximum contractile response to histamine in isolated bronchial tissue from ovalbumin-sensitized guinea pigs when used at a concentration of 1 μM. Aerosolized APC 366 (5 mg in 1 mL of water) reduces airway resistance and increases dynamic lung compliance in A. suum antigen-challenged pigs. It also reduces collagen content and expression of protease-activated receptor 2 (PAR-2) and α-smooth muscle actin (α-SMA) in rat liver in a model of bile duct ligation-induced liver fibrosis.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N2-[(1-hydroxy-
Molecular Formula
C22H28N6O4 • XCF3COOH
Formula Weight
440.5
Purity
≥95%
Formulation
A solid
Solubility
- Ethanol:Water: 5 mg/mL (in 20% EtOH)
SMILES
OC1=C(C(N[C@@H](CCCNC(N)=N)C(N2[C@H](C(N)=O)CCC2)=O)=O)C=CC3=CC=CC=C31.FC(F)(C(O)=O)F
InChi Code
InChI=1S/C22H28N6O4.C2HF3O2/c23-19(30)17-8-4-12-28(17)21(32)16(7-3-11-26-22(24)25)27-20(31)15-10-9-13-5-1-2-6-14(13)18(15)29;3-2(4,5)1(6)7/h1-2,5-6,9-10,16-17,29H,3-4,7-8,11-12H2,(H2,23,30)(H,27,31)(H4,24,25,26);(H,6,7)/t16-,17-;/m0./s1
InChi Key
FFLIQFBAKJNSSS-QJHJCNPRSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-25990-1 |
|---|---|
| Supplier Part Number | 25990-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| Energy Star | No |
| Green | No |
| Controlled | N |