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Cayman Galantamine-d3 (hydrobromide)
List Price $253.00 Your Price $253.00
Cayman Galantamine-d3 (hydrobromide) - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-26103-1
MFG.PART: 26103-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
Galantamine-d3 is intended for use as an internal standard for the quantification of galantamine by GC- or LC-MS. Galantamine is an alkaloid originally isolated from the bulbs and flowers of Galanthus that inhibits acetylcholinesterase (AChE; IC50 = 636 nM). It reverses growth inhibition and inhibits apoptosis, autophagic flux, and production of reactive oxygen species (ROS) induced by amyloid-β (Aβ) in neuronally differentiated PC12 cells. Galantamine prevents soman toxicity and inhibits acetylcholinesterase in cynomolgus macaques (ED50s = 590 and 362 μg/kg, respectively). It also decreases escape latency in the Morris water maze and the total hippocampal area of Aβ plaques in an APP/PS1 transgenic mouse model of Alzheimers disease.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
(4aS,6R,8aS)-
CAS Number
2140262-53-7
Molecular Formula
C17H18D3NO3 • HBr
Formula Weight
371.3
Purity
≥99% deuterated forms (d1-d3)
Formulation
A solid
Solubility
- Chloroform: soluble
SMILES
O[C@H]1C=C[C@]23[C@](OC4=C2C(CN(C)CC3)=CC=C4OC([2H])([2H])[2H])([H])C1.Br
InChi Code
InChI=1S/C17H21NO3.BrH/c1-18-8-7-17-6-5-12(19)9-14(17)21-16-13(20-2)4-3-11(10-18)15(16)17;/h3-6,12,14,19H,7-10H2,1-2H3;1H/t12-,14-,17-;/m0./s1/i2D3;
InChi Key
QORVDGQLPPAFRS-VKZDZIIGSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-26103-1 |
|---|---|
| Supplier Part Number | 26103-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | Y |
| CAS Number | 2140262-53-7 |
| Energy Star | No |
| Green | No |
| Controlled | N |