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Cayman SKPin C1
List Price
$134.00
Your Price
$134.00
Cayman SKPin C1 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART:
CAYM-26141-10
MFG.PART:
26141-10
UNSPSC:
12352200
Manufacturer:
Cayman
Product Description
SKPin C1 is an inhibitor of Skp1-Cullin1-F-box (SCF) family protein Skp2-mediated p27 degradation. It binds to Skp2 at the Cdc kinase subunit 1 (Cks1) interaction interface and blocks ubiquitylation of p27 in a Cks1-dependent manner in vitro when used at a concentration of 50 μM. SKPin C1 increases nuclear accumulation of p27 in ECC-1 endometrial carcinoma cells.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
2-[4-bromo-2-
CAS Number
432001-69-9
Molecular Formula
C18H13BrN2O4S2
Formula Weight
465.3
Purity
≥98%
Formulation
A crystalline solid
Solubility
- DMSO: 10 mg/mL
λmax
389 nm
SMILES
BrC1=CC=C(OCC(O)=O)C(/C=C2C(N(CC3=CC=CN=C3)C(S\2)=S)=O)=C1
InChi Code
InChI=1S/C18H13BrN2O4S2/c19-13-3-4-14(25-10-16(22)23)12(6-13)7-15-17(24)21(18(26)27-15)9-11-2-1-5-20-8-11/h1-8H,9-10H2,(H,22,23)/b15-7+
InChi Key
IYCJJVVXEHZJHE-VIZOYTHASA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-26141-10 |
|---|---|
| Supplier Part Number | 26141-10 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 432001-69-9 |
| Energy Star | No |
| Green | No |
| Controlled | N |