We use cookies to make your experience better. To comply with the new e-Privacy directive, we need to ask for your consent to set the cookies. Learn about our cookie policy.
Cayman BMS 794833
List Price $178.00 Your Price $178.00
Cayman BMS 794833 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-26180-5
MFG.PART: 26180-5
UNSPSC: 12352200
Manufacturer: Cayman


Product Description
BMS 794833 is an inhibitor of c-Met and VEGF receptor 2 (VEGFR2) with IC50 values of 1.7 and 15 nM, respectively, that also inhibits Axl, Flt3, and Ron.1,2 It inhibits proliferation of GTL-16 gastric carcinoma cells (IC50 = 39 nM) and induces tumor statsis in GTL-16 and U87 mouse xenograft models when administered at a dose of 25 mg/kg.1
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[4-[(2- amino-3-chloro- 4-pyridinyl) oxy]-3-fluoro phenyl]-5-(4- fluorophenyl)- 1,4-dihydro- 4-oxo-3-pyridine carboxamide
CAS Number
1174046-72-0
Molecular Formula
C23H15ClF2N4O3
Formula Weight
468.8
Purity
≥98%
Formulation(Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
- DMF: 17 mg/mL
- DMSO: 17 mg/mL
λmax
298 nm
SMILES
FC1=C(OC2=C(Cl)C(N)=NC=C2)C=CC(NC(C3=CNC=C(C4=CC=C(F)C=C4)C3=O)=O)=C1
InChi Code
InChI=1S/C23H15ClF2N4O3/c24-20-19(7-8-29-22(20)27)33-18-6-5-14(9-17(18)26)30-23(32)16-11-28-10-15(21(16)31)12-1-3-13(25)4-2-12/h1-11H,(H2,27,29)(H,28,31)(H,30,32)
InChi Key
PDYXPCKITKHFOZ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room Temperature in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-26180-5 |
|---|---|
| Supplier Part Number | 26180-5 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | China |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 1174046-72-0 |
| Energy Star | No |
| Green | No |
| Controlled | N |

