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Cayman CAY10736
List Price $240.00 Your Price $240.00
Cayman CAY10736 - CAYM (Additional S&H Or Hazmat Fees May Apply)
NETA PART: CAYM-26754-1
MFG.PART: 26754-1
UNSPSC: 12352200
Manufacturer: Cayman
Product Description
CAY10736 is an anticancer compound. It inhibits proliferation in a panel of melanoma and breast, pancreatic, and lung cancer cell lines (IC50s = 0.827-9.89 μM). CAY10736 inhibits migration and epithelial-to-mesenchymal transition (EMT) of A375 and B16/F10 melanoma cells in vitro in a concentration-dependent manner. It reduces the viability of spheroid A375 and B16/F10 cells (IC50s = 2.4 and 1.59 μM, respectively) and increases the production of reactive oxygen species (ROS) in these cells in a concentration-dependent manner. CAY10736 (5 mg/kg) reduces tumor growth in B16/F10 melanoma and Lewis lung carcinoma mouse models and an A375 mouse xenograft model.
WARNING This product is not for human or veterinary use.
Technical Information
Formal Name
N-[2-[[[(4-
CAS Number
2251753-61-2
Synonyms
- Compound 51
Molecular Formula
C41H59N3O3S
Formula Weight
674.0
Purity
≥90%
Formulation
A crystalline solid
Solubility
- Chloroform: soluble
- Ethanol: soluble
λmax
244 nm
SMILES
C=C1C(C(C)(C)[C@@](CC[C@]2(C)[C@]3([H])CC=C4[C@@]2(C)CC[C@]5(C(NCCNC(NC6=CC=C(OC)C=C6)=S)=O)[C@@]4([H])CC(C)(C)CC5)([H])[C@]3(C)C1)=O
InChi Code
InChI=1S/C41H59N3O3S/c1-26-24-38(6)31(37(4,5)33(26)45)16-17-40(8)32(38)15-14-29-30-25-36(2,3)18-20-41(30,21-19-39(29,40)7)34(46)42-22-23-43-35(48)44-27-10-12-28(47-9)13-11-27/h10-14,30-32H,1,15-25H2,2-9H3,(H,42,46)(H2,43,44,48)/t30-,31-,32+,38-,39+,40+,41-/m0/s1
InChi Key
DGJHGYUTHAAGAS-RRBGEOAMSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Stability
≥ 4 years
| SKU | CAYM-26754-1 |
|---|---|
| Supplier Part Number | 26754-1 |
| UM | EA |
| UNSPSC | 12352200 |
| Manufacturer | Cayman |
| MSDS URL | Click here |
| Temperature | -20 |
| Refrigerated-Frozen | Y |
| CountryOfOrigin | United States |
| ProductLine | CAYM |
| Qty | 1 |
| MinOrderQty | 1 |
| Weight | 7.000000 |
| Lead Time | 5 |
| Hazardous | N |
| CAS Number | 2251753-61-2 |
| Energy Star | No |
| Green | No |
| Controlled | N |